| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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Product Deatails
What is Benfotiamine Powder?
It is a fat-soluble analog of vitamin B1, has a higher absorption rate and bioavailability than vitamin B1, and is often used as a food supplement for diabetic complications. Benfotiamine has a direct anti-oxidant ability to prevent DNA damage.
Benfotiamine is vitamin B1 fat soluble derivatives, improve the bioavailability of water-soluble vitamin B1 low shortcomings, improve the blood and tissue concentrations of thiamine, so as to improve the curative effect.
Benfotiamine is primarily marketed as an antioxidant dietary supplement. In a clinical study with six patients, benfotiamine lowered AGE by 40%.
| Basic Information | |
| Product Name | Benfotiamine |
| Latin Name | Benfotiamine |
| Part Used | S-benzoylthiamine O-monophosphate |
| Appearance | White or off-white crystalline powder |
| Active Ingredient | Benfotiamine |
| Purity | 99% |
| CAS No. | 22457-89-2 |
| storage | cool dry place |
| level | food grade |
Product Specifications
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Item
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Specifications
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Results
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Appearance
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White or almost white crystalline powder
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Complies
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Identification
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Infrared absorption
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Consistent with the reference IR spectra
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Complies
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Thiamine
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≤0.1%
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0.05%
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pH
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2.7~3.3
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2.9
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Water
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≤1.0%
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0.15%
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Residue on ignition
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≤0.1%
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0.02%
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Related substances
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Impurity A
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≤0.15%
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Complies
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Impurity B
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≤0.3%
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Complies
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Impurity C
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≤0.15%
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Complies
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Unspecified impurity
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≤0.10%
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Complies
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Total impurities
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≤0.5%
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Complies
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Related compounds
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≤1.0%
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Complies
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Heavy metals
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≤20ppm
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Complies
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Assay
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98.0~102.0%
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99.6%
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Product Function
1. Diabetic neuropathy
Benfotiamine treatment appears to be a potential strategy for preventing diabetic nephropathy, a serious complication of diabetes that is associated with a higher risk of heart disease and mortality. High glucose concentrations lead to the accumulation of triose phosphate; this leads to biochemical dysfunction and eventual development of diabetic nephropathy.
Preclinical studies in rats show that benfotiamine prevents the accumulation of triose phosphate in diabetes, thereby inhibiting the development of kidney disease.
2. Cognitive improvement in Alzheimer's disease
Preclinical studies suggest that benfotiamine has beneficial effects on cognitive impairment in Alzheimer's disease. Benfotiamine has been shown to reduce amyloid deposits in animal models of Alzheimer's disease. However, these effects have not been demonstrated in humans. A phase II clinical trial is currently evaluating whether benfotiamine can prevent cognitive decline in people with mild cognitive impairment.
3. Overcome alcohol dependence
Chronic alcohol intake is associated with severe deficiencies of important nutrients and vitamins. Alcoholism-related thiamine deficiency is characterized by a neurological syndrome due to progressive loss of central and peripheral white matter. Although thiamine replacement is important in patients with alcohol-induced CNS injury, benfotiamine has not been shown to be effective in peripherally entering the CNS.
4. Benfotiamine for smoking
Smoking causes endothelial dysfunction, an early event in cardiovascular disease. Oxidative stress and inflammation can exacerbate this. In preclinical studies in rats, benfotiamine was found to prevent nicotine-induced vascular dysfunction. A trial in healthy volunteers showed that short-term treatment with benfotiamine partially restored macrovascular function in healthy smokers.
5. Kidney Protection
Data from rat studies suggest that benfotiamine has a protective effect on the peritoneum and residual kidney during peritoneal dialysis and uremia. According to a study published in the Journal of the American Academy of Nephrology, adding benfotiamine to the diet resulted in increased transketolase activity and decreased expression of advanced glycation end products and their receptors.
A study by Ustuner et al. Research published in Tissue and Cell found that benfotiamine supplementation may help reduce antibiotic-induced nephrotoxicity by improving oxidative stress and inflammation in renal tubular cells.
6. Anti-tumor potential
In vitro studies suggest that benfotiamine may block leukemia through a mechanism called apoptosis. Paposis is a type of programmed cell death involving the formation of cytoplasmic vacuoles. A cell culture study by researchers at Kanazawa University in Japan found that benfotiamine is a promising drug for patients with acute myeloid leukemia who are not eligible for standard chemotherapy. They also observed that benfotiamine worked synergistically with the chemotherapy drug cytarabine to eliminate myeloid leukemia cells.
7. Antioxidant properties
Benfotiamine is also a potent antioxidant with anti-inflammatory properties by inhibiting the synthesis of prostaglandins and leukotrienes.
Application Field
1. Benfotiamine is used for the prevention and treatment of vitamin B1 deficiency;Company information
Packaging & Shipping
PACKAGING:
1kg/Aluminum foil bag ,25kg/drum.Or small package as customer's requirement.
| Recommended Transportation Selections | ||
| By Air | By Express | By Sea |
| Suitable for >50kg | Suitable for sample order or <50kg | Suitable for > 300kg |
| Fast: 3-7 days | Fast: 3-10 days | Slow: 7-45 days |
| Lower than express cost | High shipping cost | Lowest cost |
| Airport to airport service | Door to door service | Port to port serviceRecommended transportation selections |
| Professional broker needed | Professional broker needed | |
Why Choose SheerHerb:
1. China's TOP 100 food companies
2.Over 10 years of experience
3.Wholly owned production plant
4.Sales to more than 120 countries
5 Highly Effective, No Preservatives, No Fat & Low Sugar
6.FCL, 2--5mt LCL, long contract, year contract available
7.Halal, Kosher, ISO 9001 certified
8.High quality products, complying with BP/USP/FCC/EU standard
9.The highest quality collagen sourced from 100% pure fish
10.Tasteless and odorless, most neutral tasting product on the market and with the best solubilityFAQ:
| Q1: Can i get some samples? |
| A: Yes, we can supply the free sample, but the shipping cost be paid by our customers. |
| Q2: How to start orders or make payments? |
| A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union |
| or Paypal or Escrow(Alibaba). |
| Q3: How to confirm the Product Quality before placing orders? |
| A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the |
| samples. You can send us your product specifications and requests,we will manufacture the products according to your requests. |
| Q4:What's your MOQ? |
| A:Our MOQ is 1kg or 10g(Different products have different MOQs). But usually we accept less quantity such as 10g on the condition that sample charge is 100% paid. |
| Q5: How about delivery leadtime? |
| A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included) |
| Q6:Is there a discount? |
| A:Different quantity has different discount. |
| Q7: How do you treat quality complaint? |
| A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, |
| we will send you free goods for replacement or refund your loss. |
| Q8: How to contact us ? |
| A:You can chat with us by Trademanager,MSN&Skype Online. You can choose your interested products and send inquiry to us. You can dial our telephone directly, you will get our reply. Send Email to us. |
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